Advances in Biochemical Engineering Biotechnology New by M. Berovic, B. Contreras, M. Dueser, N. Krieger, M. Menge, PDF

By M. Berovic, B. Contreras, M. Dueser, N. Krieger, M. Menge, D.A. Mitchel, J. Mukherjee, K.S.M.S. Raghavarao, E. Sablon, K. Schuegerl, P. Todd, E. Vandamme

A suite of papers from scientists all over the international discussing the latest themes in engineering biotechnology, and comparable chemistry, laptop technological know-how, and genetics functions.

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Extracellular administered nisin complements for the nisZB anti-sense and the nisT knock-out mutation, and results in the restoration of transcription of both nisin operons [115]. Nisin induction also resulted in a higher amount of NisI gene and an increased level of immunity [115]. The requirement of the structural nisA gene for full immunity of the nisin producer had also been recognized by Kuipers et al. [92]. In contradiction to the class II non-lantibiotic inducible bacteriocins, nisin serves a dual function of being a bacteriocin and an induction factor involved in autoregulation [92].

The requirement of the structural nisA gene for full immunity of the nisin producer had also been recognized by Kuipers et al. [92]. In contradiction to the class II non-lantibiotic inducible bacteriocins, nisin serves a dual function of being a bacteriocin and an induction factor involved in autoregulation [92]. In conclusion, the large similarity among the different systems suggests that a two-component signal transduction mechanism, including a histidine protein kinase and a regulatory protein is a common feature in the regulation of bacteriocin production.

6 Role of the Leader Peptide The bacteriocin leader peptides differ from the N-terminal signal sequences for export of proteins secreted by the sec-dependent pathway in that they lack a hydrophobic membrane-spanning stretch of 10 or more residues as well as the typical proteolytic processing site [82, 120]. Class IAI leaders are slightly positively or negatively charged and contain conserved residues such as a proline residue at position –2, a serine residue at position –6 and the so-called -F-N-L-D-V-box (Fig.

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Advances in Biochemical Engineering Biotechnology New Products and New Areas of Bioprocess Engineering by M. Berovic, B. Contreras, M. Dueser, N. Krieger, M. Menge, D.A. Mitchel, J. Mukherjee, K.S.M.S. Raghavarao, E. Sablon, K. Schuegerl, P. Todd, E. Vandamme


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